Nick Lodolo reached 500 career strikeouts on July 5, 2026, a mark that places the Cincinnati Reds left-hander among the more productive strikeout pitchers of his generation through five seasons of major league service.

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Across his MLB career as a whole, Lodolo has appeared in 87 games, posting a 26-24 record with a 4.15 ERA and 500 strikeouts over 463.2 innings pitched. All of those figures have been accumulated with a single organization.

Lodolo has spent his entire career with the Cincinnati Reds, appearing in 19 games in 2022, 7 in 2023, 21 in 2024, and 29 in 2025 before continuing into the 2026 season.

In the 2026 season, Lodolo has appeared in 10 games, going 2-2 with 42 strikeouts and a 5.05 ERA over 51.2 innings. The 500-strikeout milestone marks his fifth season of major league service since debuting in 2022.

Looking ahead, Lodolo could reach 1,500 Innings Pitched this season, with 109 outs remaining to that threshold.